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During the ailment, acetyl cholinesterase activity, a biomarker of cholinergic dysfunction increased in cerebral cortex of diabetic rats about 1.8 fold

[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Touchefeu Y, Montassier E, Nieman K, Gastinne T, Potel G, Bruley des Varannes S, Le Vacon F, de La Cochetire MF

Brain target occupancy of LY3372689, an inhibitor of the O-GlcNAcase (OGA) enzyme, following administration of single and multiple doses to healthy volunteers

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