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In a mouse model of OA induced by destabilization of the medial meniscus, hydrogen peroxide triggered siRNA release, which reduced MMP-13 and IL-1 expression in inflamed chondrocytes and mitigated synovitis, osteophyte formation, and subchondral sclerosis (Wang Q

To assess whole body energy expenditure (EE) and substrate utilization (RQ), 6- and 12-month-old mice were single-housed in the Sable Systems International Promethion Core 8-Cage metabolic monitoring System (Sable Systems

[DOI] [PubMed] [Google Scholar] 90.Meister A

Lancet 367 , 12091211 (2006)

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One of the principal mechanisms by which polyphenols confer hepatic protection is through their potent antioxidant activity