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Nagime, P

The effect was dependent on ATF4, however DNA binding analysis suggested that in tumor macrophages ATF4 was primarily impacting expression of genes involved in metabolism (37)

Further investigation into the roles of membrane tubulation and ESCPE-1 would help elucidate the precise mechanistic details of stress-induced UPS of membrane proteins

doi: 10.1016/j.expneurol.2008.12.002

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The premade transferred ECM being a novel concept, we next sought to investigate its relative contribution compared to the traditionally recognized newly synthesized ECM