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Description
Nor-epinephrine, a major catecholamine that promotes adipocyte lipolysis (83, 84), is released in response to cold stimulation from terminal neurons that innervate fat cells (83) to mediate non-shivering thermogenesis (85-87) through the activation of -adrenergic receptors (-ARs)

doi:10.1016/j.ejphar.2015.01.015 33

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To further confirm the functional significance of interface I, we mutated the residues Lys47, Lys91, Phe112, and His114 in the N domain of HGF to either glutamate or alanine

Nature Rev Genet

One potential candidate IC for cancer patients is IL-2-anti-IL-2 complex (IL-2 IC), which could extend IL-2 bioactivity from hours to days
