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The in vivo pharmacokinetic investigations showed that the drug concentration in the brain was higher with Nano structured lipid carriers (NLC) as compared to the free medication given intravenously

Nakamura K, Nakayama K, Minamoto T, Ishibashi T, Ohnishi K, Yamashita H, et al

Informed consent was obtained from all participants or their legal guardians

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As matter of fact, the activation of the Ub/proteasome pathway is directly related to the execution of the apoptotic death
