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This leads to the neutralization of their positive electrostatic charge, which may influence protein interactions with substrates, cofactors, and other macromolecules 116,117,118

Mitochondrial superoxide dismutase SOD2, but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells

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The count data were filtered to remove genes with low expression, transformed using the variance stabilizing transformation from the DESeq2 package (51), and then batch corrected using ComBat (52)

F.FinchN.Van De VorstM.BakerM.PerkersenR.et al

Further studies, including prospective study designs and more diverse populations, are required to determine causal associations between G6PD deficiency and ADHD risk and elucidate underlying biological mechanisms