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Description
Higher doses produce increased incidence and severity of gastrointestinal symptoms, which explains why clinical protocols use gradual dose escalation starting at 0.25 mg weekly and incrementally increasing every 4 weeks

Rajkumar, V

Behav Brain Res 1996

Both receptors are overexpressed in many tumor cell lines as well (Berclaz et al., supra

World sickle cell day 2016: a time for appraisal
Underlying Health Conditions (e.g., Anemia, Fatigue Disorders) Conditions like pernicious anemia, chronic fatigue, fibromyalgia, or malabsorption issues (e.g., IBS, celiac) often require ongoing support
