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Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, as they reflect whether side effects are bothersome enough to outweigh potential benefits
(1993) Mar- Apr;14(2):94-9
Does Vitamin B12 Directly Cause Weight Changes

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Rarely, hypersensitivity reactions can occur, for instance, urticaria (hives) or other allergic-type reactions have been reported in isolated cases
