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doi: 10.3389/fimmu.2024.1456145 Received 28 June 2024 Accepted 16 August 2024 Published 10 September 2024 Volume 15 - 2024 Edited by Frederick Miller, National Institute of Environmental Health Sciences (NIH), United States Reviewed by Shepherd Schurman, National Institutes of Health (NIH), United States Kenneth Michael Pollard, The Scripps Research Institute, United States Adam Schiffenbauer, National Institutes of Health (NIH), United States Updates Copyright 2024 Choi, Costenbader and Fritzler

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In a phase I trial in patients with advanced solid tumors, treatment with the IGF-1R/INSR TKI linsitinib in combination with erlotinib was well tolerated, with preliminary evidence of clinical activity, particularly in patients with NSCLC

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Kim, Y., Lin, Q., Glazer, P

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