conjugation phase glutathione phase Drug metabolism The role of glutathione-S-transferase in

It also plays a role in converting homocysteine, an amino acid, into methionine, thereby helping to maintain healthy homocysteine levels

HT1080-HMGB1-Lucia cells stably express an HMGB1::Lucia luciferase fusion protein in the cytoplasm, in which the C-terminus of the High-Mobility-Group-Protein B1 (HMGB1) is fused to the Lucia luciferase

10.3389/fpsyt.2020.00346 5

ITC experiments were performed in a Micro-Cal PEAQ-ITC (Malvern Panalytical, Worcestershire, UK) calorimeter with a stirred 206.2 L reaction cell held at 20 C

Murray RZ, Rhl J, Zaharia A, Rudolph M

Nrf2 counteracts these effects by upregulating SLC7A11, GCLC, and HO-1, enhancing glutathione synthesis and GPX4 activity while inhibiting NF-B (Zhang, 2025