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While previous imaging techniques have mainly focused on magnetic resonance spectroscopy (MRS), which detects localized concentrations of metabolites such as choline, citrate, and various amino acids, these metabolic profiles reflect tumor metabolic intensity and may indicate responsiveness to ammonium-targeted therapies (278, 279)

Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway

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It is used as a preservative, solvent, and has a floral/balsamic scent in large amounts

This review provides a comprehensive overview of recent advances in the rational design, chemical synthesis, and biological evaluation of promising XO inhibitors for the treatment of hyperuricemia and gout

This work was funded by ShanghaiTech University, the National Program on Key Basic Research Project of China (2018YFA0507004 to W.S.), National Natural Science Foundation of China (31971362, 32171439 to W.S.) and Shanghai Natural Science Foundation Grant (18ZR1425100 to X.H.)