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Epigenetic and gene expression changes related to transgenerational carcinogenesis

Mechanisms of fingolimods efficacy and adverse effects in multiple sclerosis

Nuru, M., Muradashvili, N., Kalani, A., Lominadze, D., & Tyagi, N

has received speaking honoraria and travel expenses for scientific meetings and has been a steering committee member of clinical trials or participated in advisory boards of clinical trials in the past 3 years with Actelion, Biogen, Celgene, EXCEMED, Genentech, Genzyme, Merck Serono, the Multiple Sclerosis International Federation, the National Multiple Sclerosis Society, Novartis, Roche, Sanofi-Aventis and Teva

In addition to oxidative damage, ROS can regulate epigenetic modifications, which is a heritable change in gene function without alterations in DNA sequence