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Short NJ, Kantarjian HM, Jabbour E, O'Brien S, Faderl S, Burger JA, Garris R, Qiao W, Huang X, Jain N, Konopleva M, Kadia T, Daver N, Borthakur G , Cortes JE, Ravandi F

10.1007/s12012-023-09804-7 88 IrikuraR.NishizawaH.NakajimaK.YamanakaM.ChenG.TanakaK.et al (2023)

They have not undergone the clinical trials required for FDA approval as a drug for human therapy

Alycia Halladay, chief science officer at the Autism Science Foundation, in a statement

Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (, )
L., Hollenberg S
