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Hydrogen peroxide, which is an essential factor for thyroid hormone biosynthesis, is produced in the thyroid gland by two isoform enzymes, i.e., dual oxidase 1 (DUOX1) and 2 (DUOX2), belonging to NOX family, with the most convincing experimental evidence found for DUOX2 [137,138,139]

However, in this GSH/GSSG couple, one form reduced glutathione or GSH is more important than the other

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Ward M.G., Kariyawasam V.C., Mogan S.B., Patel K.V., Pantelidou M., Sobczynska-Malefora A., Porte F., Griffin N., Anderson S.H., Sanderson J.D., Harrington D.J., Irving P.M

10.1016/j.bbadis.2020.165823 67 ShobeiriP.KarimiA.MomtazmaneshS.TeixeiraA

doi: 10.1096/fasebj.13.10.1169

For references and more information , see the section on Overnutrition and obesity in the in-depth article on Immunity