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The overall TMA polarization was found to be more M1-like in the PT group, indicating that the functions of TAMs had undergone a switch toward proinflammatory and antitumor activity

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Specifically, TfR1, GPX4, SLC7A11, SLC3A2 and SLC40A1 were significantly downregulated, while FTH/L, ACSL4, HO-1, NCOA4 and LC3II were upregulated (Fig

Sixth, the control human tissues used in this study were derived from adjacent relatively normal aortas of patients with AAA

Beyond its roles in tumor cells, MFAP2 also marks a distinct subset of CAFs in gastric cancer that exhibit immunosuppressive properties and contribute to immune evasion [59]