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Supplemental B12 favorably modulates persistently dysregulated inflammatory genes in the leukocytes of patients with VCD After 6 to 12 months from the initial diagnosis, CCL11 ( P = 0.0127) and LIF ( P = 0.0485) continued to show upregulation in leukocytes from individuals with persistent VCD compared to those from non-impaired subjects (Fig

Experts highlighted the need for healthcare education on recognizing B12 deficiency symptoms and suggested targeted prophylactic supplementation for high-risk groups

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Someya S, et al