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Endothelial dysfunction in diabetes mellitus
In contrast, IGFBP 5 tumor tissue levels have been found to be significantly associated with poor disease outcome and the addition of IGFBP 4 (measured as IGFBP 5 /IGFBP 4 ratio expression levels) further increased prognostic power [63]
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Any such combination study should be designed with appropriate controls and conducted strictly within a laboratory setting by qualified researchers
