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doi: 10.1080/17843286.2021.1996069, PMID: [DOI] [PubMed] [Google Scholar] 201.Todor TS, Fukudo S

10.1007/s13346-018-00613-y [DOI] [PubMed] [Google Scholar] Bolaman Z., Kadikoylu G., Yukselen V., Yavasoglu I., Barutca S., Senturk T

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Interestingly, LA treatment of CIA mice before onset of arthritis prevented the zonulin-induced increases in macromolecular flux as well as increasing mRNA expression of tight junction proteins

Those effects are documented in mice and cultured cells, not in people

Results are modest to meaningful rather than dramatic, they require consistent daily application over months, and they work best as part of a comprehensive hair health protocol rather than as a standalone treatment for severe hair loss