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Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries

The exact role of xCT in neuroprotection or neurodegeneration is context dependent

These histiocytes, which adopt an epithelioid morphology, manifest as well-formed granulomas [29]

Rondanelli M, Perna S, Faliva M, Monteferrario F, Repaci E, Allieri F

10.1074/jbc.M109.070201 156 WilliamsJ

23 NADPH is also needed for dihydrofolate reductase (DHFR) enzyme to catalyze the reduction of dihydrofolate to tetrahydrofolate (THF) in folate metabolism, which is required for de novo biosynthesis of thymidylate, purines, methionine, and some amino acids
