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The liver relies heavily on glutathione during its detoxification processes

doi:10.1016/0002-9343(94)90149-x

CrossRef Multicenter Phase II Study of Oxaliplatin, Irinotecan, and S-1 as First-line Treatment for Patients with Recurrent or Metastatic Biliary Tract Cancer Changhoon Yoo, Boram Han, Hyeong Su Kim, Kyu-pyo Kim, Deokhoon Kim, Jae Ho Jeong, Jae-Lyun Lee, Tae Won Kim, Jung Han Kim, Dae Ro Choi, Hong Il Ha, Jinwon Seo, Heung-Moon Chang, Baek-Yeol Ryoo, Dae Young Zang Cancer Research and Treatment.2018

Upon metabolism into SAMe, it donates its methyl group and is converted into S-adenosylhomocysteine (SAH)

In both UC and CD tissue samples, areas with high eosinophil density often exhibit locally increased expression of eotaxin and related chemokines like CCL5 (RANTES)