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Additionally, experimental models, including animal studies for various diseases, have provided insights into its multifaceted pharmacological properties (Table 1)

Hypoalbuminemia, vascular disease, and coagulopathy have all been linked to COVID-19 and have been shown to predict outcomes independent of age and morbidity [151]

Simultaneously, mitochondria also produce oxygen free radicals, called superoxide (O 2 ), non-enzymatically, which interacts with other moieties and generate reactive oxygen species (ROS), such as hydrogen peroxide (H 2 O 2 ), peroxynitrite (ONOO), and hydroxyl radical (OH )

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Although research on nano-antioxidant functional nanoparticles in the biomedical field has made notable progress, their long-term biological effects and potential risks remain insufficiently understood