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Individuals with advanced alcoholism frequently present with clinical liver disease while reporting low perceived intoxication levels, precisely because neuroadaptive tolerance has altered CNS GABA-ergic and noradrenergic baseline signaling

doi: 10.3389/fmed.2021.620990 67 OffringaAKBourgonjeARSchrierMSDethRCvan GoorH

Research shows that increasing GABA levels may help improve insomnia (21)
