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According to a study published in PubMed Central (National Institutes of Health), intravenous administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency
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To mimic this metabolic stress in vitro, SCs were cultured under glucose deprivation

The authors thank the So Paulo Research Foundation FAPESP (Grants #2017/07351-4 and #2023/11496-9) and National Council for Scientific and Technological Development CNPq (Grant #409498/2021-1) for funding the study

Disrupted fronto-parietal network and default-mode network gamma interactions distinguishing suicidal ideation and suicide attempt in depression

Early observations suggest that it may interact with signaling pathways involved in maintaining cellular structure and function in preclinical models
