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Laboratory animal studies have also indicated that ethanol metabolism is decreased and toxicity increased with advancing age [10-13]

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Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity

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Fe(III)-Shikonin supramolecular nanomedicine for combined therapy of tumor via ferroptosis and necroptosis

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Nature 485 , 459464 (2012)

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M.ShenD

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Similar calculations for the reaction between HSA-SOH and GSH give an estimated HSA-SOH half-life of 4 min

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