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Shaydakov ME, Comerota AJ, Lurie F
Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food. Diabetes, vol
Pike CJ
1 Accumulating ACs are thought to deplete the carnitine stores because of increased urinary excretion and an inhibitory effect on OCTN2, lowering the renal excretion threshold for free carnitine
Overall, this network-based analysis highlights interconnected metabolic and gene regulatory pathways that may contribute to ASD-associated metabolic dysregulation and offers a systems-level framework for prioritizing pathways for future mechanistic and validation studies
Other conditions that cause carnitine deficiency include angina (chest pain) and intermittent claudication (cramping leg pain from blocked arteries) [6]
