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The included preclinical studies demonstrated consistently positive effects across diverse injury models including tendon rupture, ligament tears, muscle injuries, bone fractures, and combined soft tissue trauma

They stimulate repair processes so early benefits may be subtle, but cumulative

Emerging approaches that modulate noncoding RNAs, including miRNA mimics or inhibitors and antisense oligonucleotides targeting lncRNAs, have shown some promise in animal models, but further validation is still needed 197,198,199

Drug Targets 8 , 325331 (2007)

Treatments with DSIP and DSIP-CBBBP are shown to effectively increase melatonin levels, indicating a stress-mitigating potential, whereas CBBBP treatment alone does not significantly affect melatonin levels, pointing to its limited efficacy in this context