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All animal experiments were approved by the Animal Experiments Committee of LUMC and performed according to the recommendations and guidelines set by LUMC and by the Dutch Experiments on Animals Act (permit number AVD1160020186804)

By week 4, many of these patients have moved from significant functional impairment from GI symptoms to largely resolved or substantially reduced symptom burden

Tips for patients Here are some tips for patients before starting treatment: Keep monitoring your energy levels, B12 levels, and any neuropathy symptoms

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Vitamin B12 plays a vital role in the body Including maintaining the health of your nerves Red blood cells and DNA Deficiencies in vitamin B12 can lead to anemia Neurological symptoms, and fatigue Some individuals may have trouble absorbing B12 through their diet or have a condition that prevents proper absorption, such as pernicious anemia