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However, some of the studies in the literature have low reliability due to limited sample size, lack of a control group, or being pilot studies

Differences in experimental methods, data formats, and recording practices across research institutions create significant barriers to cross-institutional data integration [639, 655]

These are subsequently converted by superoxide dismutase (SOD) into hydrogen peroxide (HO), which can further react with ferrous iron (Fe 2 ) via the Fenton reaction to generate highly reactive hydroxyl radicals (OH)
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