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Moreover, only 54% of patients in those economics have access to oral cysteamine therapy, and there is limited access to cysteamine eye drops, supportive therapies, and standard diagnostic and monitoring tools, all of which are essential for the prevention of disease progression and extended lifespan [159]

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Such interactions lead to the formation of an immune-inhibiting TME, allowing cancer cells to escape immune surveillance [39, 40]

Lab testing, including G6PD screening (prior to high-dose vitamin C), kidney function, and electrolyte monitoring, is essential to ensure safety