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In addition, propionic acid, and to a lesser extent butyric acid, modulates the expression of genes associated with ASD, including cell adhesion molecules (neurexin 1 and neuroligin), neurotransmitter systems, mitochondrial, redox, immune, and FMR1 genes in PC12 cells (172)

61 Many of those experiments that had trouble finding an increase in TMAO after carnitine challenges lacked adequate timing or used only a moderate amount of red meat, whereas studies that included a significant carnitine load from red meat have shown clearer TMAO elevation

Baird, GS

[DOI] [PubMed] [Google Scholar] Zimmerman HJ, Ishak KG