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Instead, it is mediated through the systemic administration of CB 1 agonists acting on peripheral CB 1 receptors, resulting in hypotension due to the inhibition of noradrenaline release from postganglionic sympathetic neurons (Niederhoffer et al., 2003)

10.1378/chest.125.2.509 131 MugabeC.AzghaniA

& Jahnke, W

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Nagata, K

RESULTS: Overall, 3417 participants underwent randomization
