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10.1186/s13046-019-1259-z J Exp Clin Cancer Res

NAC, a precursor to glutathione, is a powerful cellular antioxidant used as free radical scavenger antioxidant in its own right

Similarly, Mrp2 has also been reported to mediate the biliary excretion of mycophenolic acid-7-O-glucuronide, 4-methylumbelliferyl glucuronide, flavopiridol glucuronide, grepafloxacin glucuronide, 17-estradiol-17--D-glucuronide, and resveratrol glucuronide (Sasabe et al., 1998

Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]

Orti DL, Hill RH, Liddle JA et al (1986) High performance liquid chromatography of mycotoxin metabolites in human urine

(1984) Idiosyncracies of drug metabolism in cats