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The reduction of mitochondrial ROS production dramatically decreases the cross-presentation capacity of pDCs, leading to a strong reduction of their capacity to trigger CD8 + T cells responses (101)

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[DOI] [PMC free article] [PubMed] [Google Scholar] [12].Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG, Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Nature 336(6197):385388 Christopherson KS, Hillier BJ, Lim WA, Bredt DS (1999) PSD-95 assembles a ternary complex with theN-Methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain

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