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Relevant antibody subsets against MOG recognize conformational epitopes exclusively exposed in solid-phase ELISA

10.3390/ijms21124484 356 PruimboomL.MuskietF

This process promotes LPO, leading to ferroptosis owing to ROS produced by mitochondria

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A critical event for mitochondrial apoptosis is the release of CYCS or AIFM1/AIF (apoptosis inducing factor mitochondria associated 1) from the mitochondria, which mediates apoptosis through activating caspases (e.g., CASP9 [caspase 9]) or endogenous endonucleases, respectively [75,76]

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