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Neuronal excitability due to amplified responses of the CNS to peripheral input has led to central sensitization (CS) being proposed to be involved in the pathophysiology of fibromyalgia (Fig

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The dominant role of oxygen in modulating the chemical evolution pathways of tyrosine in peptides: Dityrosine or melanin

Collectively, existing research shows that GSK-3 is a key node related to aging and aging-related diseases, particularly in terms of the regulatory network centered on the GSK-3 /Nrf2 axis

Mitochondrial fission Mitochondrial division mediated by dedicated cellular factors called dynamin-related protein 1 (DRP1 and mitochondrial fission factor (Mff)

Histamine is a key player in regulating the sleep-wake cycle
