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Drug-drug interactions are among the leading causes of adverse drug reactions (ADRs)
The glutamine antagonist prodrug JHU-083 slows malignant glioma growth and disrupts mTOR signaling
Therefore, these results demonstrate that the interaction of PRDX1 with DOK3 induces attenuation of DOK3 degradation, leading to inhibition of plasma cell differentiation
Among them, the most clinically successful NRF2 activator is dimethylfumarate (DMF), authorized in Germany in 1994 for the treatment of psoriasis [281]
