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The upregulation of mitochondrial uncoupling protein 2 (UCP2) leads to tissue hypoxia by activating HIF-1, which in turn stimulates lipid deposition and ECM accumulation, thereby promoting RF [67]

The free energy change for the conversion of glutamate to alpha ketoglutarate is 3.7 kcal/mol (4)

Our results are consistent with those of previous studies and indicate that ferroptosis induction is an effective therapeutic strategy for GBM

doi: 10.1016/j.celrep.2022.111755 61 MeiJLiuYDaiNHoffmannCHudockKMZhangPet al
The comparative anti-oxidant and anti-inflammatory efficacy of postbiotics and probiotics through Nrf-2 and NF-kB pathways in DSS-induced colitis model

HW: Conceptualization, Data curation, Writing review & editing
