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However, emergence of drug resistance mutations (DRMs) can greatly affect treatment outcomes and impede virological cure
Others such as the phenothiazines and minocycline may be deposited in the skin or mucosa and directly react with melanin to form a drugpigment complex
LPL binds to its endothelial coenzyme, glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), to provide a platform for lipolysis of apoB-containing lipoproteins on the surface of vascular endothelium (Davies et al., 2010
Furthermore, decreased LDL cholesterol uptake by the liver could be an alternative mechanism contributing to increased LDL cholesterol concentrations [41]
[PubMed: 19901191] 829
