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no therapeutic intervention trials published Cell culture Skeletal muscle myoblasts, cardiomyocytes, endothelial cells, fibroblasts, mesenchymal stem cells Ex vivo tissue preparations Isolated mitochondria, cardiac tissue preparations for respiration studies Research Limitations & Regulatory Status Critical Gaps in Current Evidence Despite over 100 published preclinical studies and growing scientific interest, MOTS-c faces substantial translational barriers that limit clinical application and necessitate cautious interpretation of its therapeutic potential

204 YangT.IreneK.LiuH.LiuS.ZhangX.XuM.et al (2019)

She was diagnosed with chronic immune thrombocytopenia purpura (ITP), an autoimmune blood disorder requiring ongoing infusions or steroid treatment

The reaction was measured at 450 nm, with a detection range of 0.31220 nmoL/mL

[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Tan V.P.Y., Wong B.C.Y
