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Recently, we have also reported a direct link between antibodies to Glo-3a (a wheat-related protein), zonulin upregulation, and islet autoimmunity in children at increased risk for T1D (12)

In addition to these, several novel enzyme inhibitors have shown promise

Watanabe M, Hida A, Kitamura S, Enomoto M, Ohsawa Y, Katayose Y, et al

Circulation , 144 22, 1795-1817

Finally, the benzothiazole Riluzole, which enhances EAAT2 expression and glutamate clearance, has been approved and shown modest beneficial effects on ALS progression 447,448

Anderson G
