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Although keeping sulfide concentrations in the narrow therapeutic range appears to be critical, currently available pharmacological tools (e.g., inhibitors of H 2 S-producing enzymes) fail to achieve this goal

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Rommel C, Clarke BA, Zimmermann S, Nunez L, Rossman R, Reid K, Moelling K, Yancopoulos GD, Glass DJ (1999) Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt

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Zhou W, Mukherjee P, Kiebish MA, Markis WT, Mantis JG, Seyfried TN

doi: 10.1007/s00018-015-2070-4 67 SuzukiMSasabeJMiyoshiYKuwasakoKMutoYHamaseKet al