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(2011) investigated L-carnitine supplementation in human subjects and observed increased muscle carnitine content and changes in fuel utilization during exercise, demonstrating that chronic supplementation can alter the muscle carnitine pool [2]

These effects are usually mild and disappear with dosage adjustment

Ultimately, CPT2 on the inner mitochondrial membrane converts LCACs to free carnitine and long-chain acyl-CoA
Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al
They either consumed eight 10-gram doses of whey every 1.5 hours, or four 20-gram doses of whey every 3 hours, or two 40-gram doses every 6 hours