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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Montero D., Walther G., Stehouwer C.D.A., Houben A.J.H.M., Beckman J.A., Vinet A

The offspring of two heterozygotes has a 1 in 4 chance of being homozygous for the sickle mutation, a state that produces symptomatic sickle cell disease, which afflicts 70,000 to 100,000 individuals in the United States

doi: 10.1089/neu.2012.2535

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FTIR spatial resolution is typically in the approximately 1020 m range, which biases datasets toward larger particles and contributes to systematic underdetection of the low-micrometre fraction [12]