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Exogenous mPTP inhibitor CsA, when interacting with CypD, prevented Ca 2+ -induced CypD from combining with ANT and inhibited Ca 2+ mitochondrial output, which gave rise to decreased m, and blocked ROS production

Cysteine metabolic circuitries: Druggable targets in cancer

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Notably, Ganoderma lucidum extracts exhibited significant tyrosinase inhibition, with an IC50 value of approximately 0.32 mg/mL, indicating the concentration required to achieve 50% inhibition of enzyme activity