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Vitamin C plays a role in synthesizing and regulating certain hormones, including those involved in stress response and metabolism [286,287,288,289]

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Importantly, lifespan extension from haao-1 knockdown was not completely abrogated by skn-1 loss-of-function, and also showed a complex and temperature-dependent interaction with other aging pathways, suggest that a complete mechanistic model is multi-faceted

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Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation
