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Chinese Herbal Monomers (HMs) and Their Derivatives: Mechanisms The therapeutic mechanism of HMs involves reducing inflammatory and vascular growth factor levels, regulating Ca 2+ and K + channels, restoring mitochondrial function, and controlling signaling pathways to achieve pulmonary artery vasodilation, protect endothelial function, and reverse PVR
Amer J Physiol Heart Circ Physiol 292: H2023H2031
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Suggestive but not definitive evidence
Pietrelli A, Matkovi L, Vacotto M, Lopez-Costa JJ, Basso N, Brusco A
