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In animal toxicology studies, no significant adverse effects have been observed even at doses far exceeding typical therapeutic ranges

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Therefore, LPS-PLGA NPs can efficiently shift Th1 to Th2/Treg (Khakzad et al., 2019)

Xiang X, Liu Y, Zhang X, Zhang W, Wang Z

As interest grows, it becomes increasingly important to examine both the scientific evidence and practical considerations surrounding this therapy

Johnstone TB, Gu Z, Yoshimura RF, Villegier AS, Hogenkamp DJ, Whittemore ER, et al
