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Extensive preclinical validation has underscored the significant potential of O-GlcNAcylation as a therapeutic target in neurodegenerative diseases, sparking great research interest among multiple companies seeking OGA inhibitors
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[DOI] [PubMed] [Google Scholar] 177.Luo Y., Wang W., Zeng Y., Wang S., Guo X., Hu R., Yang G

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Absolute changes in IL-8, IL-10, TNF-, FEV 1 %pred and FEV 1 /FVC were significantly greater after ambroxol treatment, suggesting that large doses of ambroxol may have anti-inflammatory effects that facilitate lung function recovery
