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doi: 10.1101/gad.271130.115 17 CheungE

People are more unhealthy than ever before, and more people are diagnosed with diabetes than ever before, which means you might potentially be developing insulin resistance without showing any symptoms at this moment

Hepatic insulin resistance following chronic activation of the CREB coactivator CRTC2

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The Del allele in this polymorphism is linked to a reduction in promoter activity which can result in decreased synthesis of the SOD1 enzyme, compromising the its ability to neutralize O 2 - radicals (Mirsadraee and Saadat, 2019