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This essential endogenous antioxidant, which cells make, actively contributes to the elimination of free radicals and reactive oxygen species [6]

The metabolic acidosis and the 5-oxoprolinuria in these patients are explained by the decreased feedback inhibition of -glutamylcysteine ligase resulting from the lower GSH levels

addition of lipid standards using LipoStar DB manager)

doi: 10.5352/JLS.2017.27.11.1315 401 WeiCZhangFSongLChenXMengX

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Figure 1 provides a summary of the pathways and demonstrates which pathways are targeted by the better studied treatments